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Package: pleiosim
Type: Package
Title: Simulation of Pleiotropic Genotypes and Phenotypes
Version: 0.2.0
Authors@R:
person("Wanjun", "Gu", ,email = "wanjun.gu@ucsf.edu", role = c("aut", "cre"),
comment = c(ORCID = "0000-0002-7342-7000"))
Description: The 'pleiosim' package provides tools for simulating pleiotropic genetic data,
including the generation of genotypes, simulation of heritable and non-heritable phenotypes,
and calculation of summary statistics. It allows for flexible customization of genetic
architecture, including effect allele frequencies, effect size matrices, heritability,
and correlation structures between traits. The package supports modeling pleiotropy,
cross-trait heterogeneity, within-trait heterogeneity, and simulating diverse cohort
compositions. It is designed to facilitate research on the genetic architecture of complex traits, pleiotropy, and multi-trait genetic analysis.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.2