diff --git a/crates/transpiler/src/passes/constrained_reschedule.rs b/crates/transpiler/src/passes/constrained_reschedule.rs
index 54bbabafa6bb..a7280094f766 100644
--- a/crates/transpiler/src/passes/constrained_reschedule.rs
+++ b/crates/transpiler/src/passes/constrained_reschedule.rs
@@ -208,7 +208,7 @@ fn push_node_back(
 
         // Compute overlap if there is qubits overlap
         let qreg_overlap = if !this_qubits.is_disjoint(&next_qubits) {
-            new_t1q - next_t0q
+            new_t1q.saturating_sub(next_t0q)
         } else {
             0
         };
@@ -219,7 +219,7 @@ fn push_node_back(
             && !this_clbits.is_disjoint(&next_clbits)
         {
             if let (Some(t1c), Some(t0c)) = (new_t1c, next_t0c) {
-                t1c - t0c
+                t1c.saturating_sub(t0c)
             } else {
                 0
             }