What is Helix

Helix helps you organize, analyze, and visualize scientific data from raw numbers to publication-ready charts — powered by three trusted open-source engines: Jspreadsheet CE for tables, WebR (R running in WebAssembly) for statistics, and Plotly for graphs. Think of it as a free, minimalist alternative to GraphPad Prism. Built with Glaze.

Note: this is a foundation in active development. Feedback, bug reports, and feature requests are welcome.

Key Features (non-exhaustive)

Data Organization

• Three-pillar structure — Tables → Analyses / Graphs, with every analysis and graph linked back to its source table
• 4 table types — Column, XY, Grouped, Multiple Variables
• Spreadsheet-style grid — Copy/paste, undo/redo, multi-cell selection, row/column deletion
• Data exclusion — selectively exclude data points from graphs and statistical analyses

Statistical Analyses

• Smart guided wizards for test selection based on your table type
• Descriptive statistics
• Compare two groups — Student's t test, Welch's t test, Mann-Whitney, paired t test, Wilcoxon
• Compare multiple groups — One-way ANOVA, Kruskal-Wallis, repeated-measures ANOVA, Friedman test
• Post-hoc tests — Tukey, Bonferroni, Dunn's test
• One-sample t test, correlation & correlation matrix
• Linear regression and nonlinear regression (straight line, sigmoidal 4PL, semilog, hyperbola, polynomials)
• Two-way ANOVA
• Multiple regression and multiple t tests
• Multiple-comparison corrections — Holm, FDR (Benjamini-Hochberg)

Graphs

• Chart types — Individual values, box plots, violin plots, scatter, line, bars, area, stacked bars
• Interactive rendering — zoom in and out, adjust axes thickness and font size
• Axis control — Manual or automatic min/max/step
• Error bars — SD, SEM, or none
• Significance annotations — Stars or p-values with pairwise comparisons
• Export to PNG, JPG, or SVG; copy to clipboard

Projects & Interface

• Native .hlx project format (JSON-based, fully portable) — open and edit with any text editor
• Native menu bar with keyboard shortcuts
• Decimal separator conversion — automatically convert commas to periods in all spreadsheet numbers (required for R compatibility)
• Light, dark, or automatic theme

Screenshots